Phoenix street circuit · 10 March 1991
Ayrton Senna won the 1991 United States Grand Prix for McLaren from 1st on the grid, 16.322s ahead of Alain Prost. Aguri Suzuki gained the most places, from 21st on the grid to 6th.
| Pos | Team | Points Breakdown | Pts | |
|---|---|---|---|---|
| 1 | McLaren Senna 10 + Berger 0 | Senna 10 + Berger 0 | 10 | |
| 2 | Ferrari Prost 6 + Alesi 0 | Prost 6 + Alesi 0 | 6 | |
| 3 | Tyrrell Modena 3 + Nakajima 2 | Modena 3 + Nakajima 2 | 5 | |
| 4 | Benetton Piquet 4 + Moreno 0 | Piquet 4 + Moreno 0 | 4 | |
| 5 | Lola Suzuki 1 + Bernard 0 | Suzuki 1 + Bernard 0 | 1 | |
| 6 | Lambo Larini 0 | Larini 0 | 0 | |
| 7 | AGS Tarquini 0 | Tarquini 0 | 0 | |
| 8 | Minardi Martini 0 + Morbidelli 0 | Martini 0 + Morbidelli 0 | 0 | |
| 9 | Jordan Gachot 0 | Gachot 0 | 0 | |
| 10 | Brabham Brundle 0 + Blundell 0 | Brundle 0 + Blundell 0 | 0 | |
| 11 | Team Lotus Häkkinen 0 | Häkkinen 0 | 0 | |
| 12 | Williams Patrese 0 + Mansell 0 | Patrese 0 + Mansell 0 | 0 | |
| 13 | Footwork Alboreto 0 | Alboreto 0 | 0 | |
| 14 | Leyton House Capelli 0 + Gugelmin 0 | Capelli 0 + Gugelmin 0 | 0 | |
| 15 | Ligier Boutsen 0 | Boutsen 0 | 0 | |
| 16 | Dallara Pirro 0 + Järvilehto 0 | Pirro 0 + Järvilehto 0 | 0 |
| Pos | Driver | Team | Race time / Gap | Laps | Stops | Pts | |
|---|---|---|---|---|---|---|---|
| 1 | Ayrton Senna McLaren | McLaren | 2:00:47.828 | 81 | — | 10 | |
| 2 | Alain Prost Ferrari | Ferrari | +16.322s | 81 | — | 6 | |
| 3 | Nelson Piquet Benetton | Benetton | +1:17.376 | 81 | — | 4 | |
| 4 | Stefano Modena Tyrrell | Tyrrell | +1:25.409 | 81 | — | 3 | |
| 5 | Satoru Nakajima Tyrrell | Tyrrell | +1 Lap | 80 | — | 2 | |
| 6 | Aguri Suzuki Lola | Lola | +2 Laps | 79 | — | 1 | |
| 7 | Nicola Larini Lambo | Lambo | +3 Laps | 78 | — | — | |
| 8 | Gabriele Tarquini AGS | AGS | +4 Laps | 77 | — | — | |
| 9 | Pierluigi Martini Minardi | Minardi | DNF Engine | 75 | — | — | |
| 10 | Bertrand Gachot Jordan | Jordan | DNF Engine | 75 | — | — | |
| 11 | Martin Brundle Brabham | Brabham | +8 Laps | 73 | — | — | |
| 12 | Jean Alesi Ferrari | Ferrari | DNF Gearbox | 72 | — | — | |
| DNF | Mika Häkkinen Team Lotus | Team Lotus | DNF Engine | 59 | — | — | |
| DNF | Riccardo Patrese Williams | Williams | DNF Gearbox | 49 | — | — | |
| DNF | Roberto Moreno Benetton | Benetton | DNF Collision | 49 | — | — | |
| DNF | Michele Alboreto Footwork | Footwork | DNF Engine | 41 | — | — | |
| DNF | Ivan Capelli Leyton House | Leyton House | DNF Gearbox | 40 | — | — | |
| DNF | Thierry Boutsen Ligier | Ligier | DNF Engine | 40 | — | — | |
| DNF | Gerhard Berger McLaren | McLaren | DNF Fuel pump | 36 | — | — | |
| DNF | Nigel Mansell Williams | Williams | DNF Gearbox | 35 | — | — | |
| DNF | Maurício Gugelmin Leyton House | Leyton House | DNF Gearbox | 34 | — | — | |
| DNF | Mark Blundell Brabham | Brabham | DNF Spun off | 32 | — | — | |
| DNF | Emanuele Pirro Dallara | Dallara | DNF Gearbox | 16 | — | — | |
| DNF | Gianni Morbidelli Minardi | Minardi | DNF Gearbox | 15 | — | — | |
| DNF | Jyrki Järvilehto Dallara | Dallara | DNF Gearbox | 12 | — | — | |
| DNF | Éric Bernard Lola | Lola | DNF Engine | 4 | — | — |